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Abe, S. Suda, S. Okubo, T. Nagao, K. Kimura, Low risk of ICH after reperfusion therapy in acute stroke patients treated with direct oral anti-coagulant, J.
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You will receive your order in three to five business days. Skip to main contentSkip to articleKeywordsIntroductionSection snippetsChemicals and materialsData analysis of pseudovardenafil and hydroxyvardenafil metabolitesDiscussionConclusionsDeclaration of Competing InterestAcknowledgementReferences (11)View full text Phosphodiesterase type 5 (PDE-5) is an enzyme that hydrolyzes cyclic guanosine monophosphate.
| Dosage (mg) | Onset Time | Duration of Effect | Suitable for | Common Side Effects |
|---|---|---|---|---|
| 10 | 30-60 min | 4-6 hours | Most men | Headache, flushing, dizziness |
| 20 | 30-60 min | Up to 6 hours | Severe ED | Nasal congestion, upset stomach |
| 5 | 45-90 min | 3-4 hours | Mild ED | Dizziness, mild nausea |
| 25 | 30 min | 6 hours | Severe ED | Flushing, minor vision changes |
Sildenafil, vardenafil, and tadalafil potentiate the effect of NO by inhibiting the enzyme, leading to enhanced vasodilation and increased blood flow.
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